PFIZER
WHEN WAS IT APPROVED? December 11, 2020
WHO CAN GET IT? Anyone aged 16 or older
DOSAGE 2 doses, 21 days apart
HOW DOES IT WORKUses messenger RNA to deliver some of the virus’s genetic code to ‘teach’ the body to make a protein that triggers the production of antibodies
HOW EFFECTIVE IS IT …
AFTER 2 DOSES: 95% effective in preventing disease; 100% effective in preventing death from COVID-19; 87% effective in preventing hospitalization
AFTER THE FIRST DOSE: (not recommended) ~ 46% effective at preventing infection seven to 20 days later; 57% effective against symptomatic diseases; 72% effective in preventing death; 74% effective against hospitalization; 62% effective against serious diseases (based on field data from Israel)
AGAINST VARIANTS OF …
UK – B117: No significant impact
South Africa – B1351 10% less effective; still protective
Brazil – P1: 10.4-fold weaker antibodies; still protective
MODERN
WHEN WAS IT APPROVED? December 18, 2020
WHO CAN GET IT? Anyone 18 or older
DOSAGE 2 doses, 28 days apart
HOW DOES IT WORKUses messenger RNA to deliver some of the virus’s genetic code to ‘teach’ the body to make a protein that triggers the production of antibodies
HOW EFFECTIVE IS IT …
AFTER 2 DOSES: 94% effective in preventing disease; 100% effective in preventing death from COVID-19; 89% effective in preventing hospitalization
AFTER THE FIRST DOSE: (not recommended) ~ 80% effective based on research data
AGAINST VARIANTS OF …
UK – B117: No significant impact
South Africa – B1351: 10% less effective; still protective
Brazil – P1: More data needed
JOHNSON & JOHNSON
WHEN WAS IT APPROVED? February 27, 2021
WHO CAN GET IT? Anyone 18 or older
DOSAGE 1 dose
HOW DOES IT WORKUses a harmless, inactivated cold virus to deliver a piece of spike protein into the body to teach it to fight SARS-CoV-2
HOW EFFECTIVE IS IT …
AFTER A SINGLE DOSE: 72% worldwide; 86% in the US.
AGAINST VARIANTS OF …
UK – B117: No significant impact
South Africa – B1351: 64% effective
Brazil – P1: 85% effective