Studies on the South African coronavirus strain raise concerns about the immune response

JOHANNESBURG – Three new laboratory studies raise concerns that the immune response triggered by a Covid-19 infection or vaccination may be less effective at protecting against the new strain of the coronavirus that first emerged in South Africa.

The findings come from laboratory experiments and look only at certain elements of a body’s immune response. Still, they reinforce the possibility that vaccine makers and regulators will need to update Covid-19 vaccines as the virus evolves.

A fourth study conducted by scientists from BioNTech SE and Pfizer Inc. and published by the companies, showed that their vaccine successfully neutralized a variant that was initially discovered in the UK. That study did not include the South African tribe.

The British variant has already spread to many other countries, including the US.

More than a year after the pandemic, the discovery of new variants that appear to have made the virus more contagious is forcing researchers to adjust their understanding of the coronavirus that causes Covid-19. One concern, researchers said, is that the new strains are emerging in countries where a significant percentage of people have already built up an immune response to previous variants after receiving Covid-19.

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