- The obesity rate in the US has skyrocketed over the past decade and is currently at an all-time high.
- Clinical trials with the drug semaglutide found that obese patients lost an average of 33 pounds in just over a year.
- The drug company Novo Nordisk has already applied for FDA approval to use the drug – currently used to combat type 2 diabetes – as an anti-obesity drug.
The obesity rate in America has skyrocketed in recent years, mainly because unhealthy eating habits and sedentary lifestyles are more common today than ever before. Consider this: The obesity rate in the US in 2021 is nearly 30% higher than in 2008. In addition, recent health data shows that a whopping 42% of all Americans are currently obese. Incidentally, 2020 was the first time that the percentage of overweight in the United States exceeded the 40% threshold. In light of the above, it is no surprise that heart disease remains the leading cause of all deaths in the US
While exercise and a healthy diet remain the best plan of attack in the fight against obesity, not everyone is able to absorb these lifestyle changes due to financial or health considerations. However, a new drug may be just the answer people are looking for.
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The drug in question is called semaglutide and is already being used as a treatment for type 2 diabetes. However, recent clinical studies show that administering a higher dose of the drug can help obese individuals lose weight.
According to a study recently published in the New England Journal of Medicine, the drug helped people lose an average of 15% of their body weight after 68 weeks. To put that in context, someone who is 300 pounds could lose more than 45 pounds in just over a year while on semaglutide. In addition, more than 33% of the study participants reported losing 20% of their body weight while taking the drug. The average amount of weight loss by study participants was about 34 pounds.
MedPageToday adds:
In addition to weight loss, semaglutide also improved cardiovascular risk factors, including greater reductions in waist circumference, BMI, systolic and diastolic blood pressure, HbA1c, fasting plasma glucose, C-reactive protein, and fasting lipid levels, as well as physical function and quality of life scores.
“This is a major breakthrough for improving the health of obese people,” said University College London professor Rachel Batterham of the study. “No other drug has reached this level of weight loss – this is truly a game changer. For the first time, people can achieve with drugs what was only possible through weight-loss surgery. “
Researchers note that the improvements seen in patients on semaglutide are much greater than what the current anti-obesity drugs on the market offer. The medication schedule itself is not very heavy and requires a person to take a single pill only once a week.
In the aftermath of the successful clinical trial, drug company Novo Nordisk is currently seeking FDA approval to use the drug as a weight loss drug.